Beta-2 Microglobulin (B2M)
| Availability | Discontinued; Replaced with 126-15 |
| Product Name | Beta-2 Microglobulin |
| Source | Human Urine |
| Catalogue Number | 126-11 |
| Purity | > 98% (SDS-PAGE) |
| Form | Lyophilized |
| Protein | Reported in mg/vial (E0.1%280 nm=1.65) |
| Formulation | Lyophilized from 0.02 M ammonium bicarbonate. May contain traces of buffer salts. |
| Appearance | White powder |
| Reconstitution | Phosphate buffered saline, pH >7.0 |
| Related Products | GB2-80A - anti-Human B2M polyclonal antibody 126-12 - B2M antigen from human urine - Liquid 431-11 - Myoglobin antigen from human heart |
| Storage | 2-8°C |
| Recertification | 5 years |
| Infectious Disease Testing | Negative or non-reactive at the donor level for anti-HIV 1 and 2, anti-HCV, HBsAg, and syphilis by FDA approved methods. |
| Molecular Weight | ~12,000 |
| Synonyms | B2M, BMG |
| UNSPSC code | 51131907 |
| Gene | B2M, CDABP0092, HDCMA22P |
| Gene ID | 567 |
| Accession No | P61769 |
| References | Nature Medicine volume 21, pages 932–937 (2015) |
Lee Biosolutions is the leading producer and supplier of Human Urine Beta-2 Microglobulin (B2M) for use in medical autoimmune research and manufacturing of clinical diagnostic assays.
Custom preparations, technical support, bulk quantities and aliquoting available, email Info@leebio.com for more details.
Serum beta-2 Microglobulin, an endogenous marker for renal function, has been shown to be an independent predictor of mortality in older adults. The characteristics of B2M make it useful as a tumor marker for some blood cell cancers, for detecting kidney damage, and for distinguishing between glomerular and tubular disorders of the kidney. It is not diagnostic for a specific disease, but it gives the doctor additional information about someone's likely prognosis and about the health of their kidneys.
