Alpha-1 Antitrypsin (A1AT)
| Product Name | Alpha-1-Antitrypsin |
| Source | Human Plasma |
| Catalogue Number | 106-11 |
| Purity | > 95% (SDS-PAGE) |
| Form | Lyophilized |
| Protein | Reported in mg/vial (A280, E0.1%=0.433) |
| Formulation | Lyophilized from sodium phosphate buffer |
| Reconstitution | De-ionized H2O |
| Storage | -20°C |
| Recertification | 3 years |
| Molecular Weight | ~54,000 |
| UNSPSC code | 51131904 |
| Synonyms | A1AT, Alpha-1 protease inhibitor, Alpha-1-antiproteinase |
| References | Identification of carbamylated alpha 1 anti-trypsin (A1AT) as an antigenic target of anti-CarP antibodies in patients with rheumatoid arthritis, Journal of Autoimmunity, Volume 80, June 2017, Pages 77-84. |
Lee Biosolutions is the leading supplier of human plasma Alpha-1-Antitrypsin (A1AT) for medical research and diagnostic manufacturing.
Custom preparations, technical support, bulk quantities and aliquoting available, email Info@leebio.com for more details.
Human alpha 1 Antitrypsin or Human A1-antitrypsin (A1AT), also known as serum trypsin inhibitor, protects tissue from enzymes from inflammatory cells, especially elastase and is present in human blood. Disorders of the enzyme include human alpha-1 antitrypsin deficiency, a hereditary disorder in which lack of Human alpha-1 Antitrypsin AAT (A1AT) leads to uninhibited tissue breakdown during inflammation.
Studies indicate that this causes pulmonary emphysema and leads to liver cirrhosis in severe cases. Human alpha-1 antitrypsin protects the lungs from the harmful effects of human neutrophil elastase.
Lee Biosolutions, Inc
