Glutamate Dehydrogenase (GLDH)

Catalogue Number: 260-10
Product Name Glutamate Dehydrogenase
Source Bovine Liver
Catalogue Number 260-10
Purity Purified
Form Lyophilized
Activity > 15 U/mg
Unit Definition One unit catalyzes the oxidation of one micromole of NADH and the reductive amination of one micromole of alpha-ketoglutarate per minute at 37°C and pH 7.95 in the presence of ADP.
Protein > 0.25 mg protein/mg (Coomassie)
Specific Activity > 20 U/mg protein
Contaminants AST/SGOT: < 5%
ALT/GPT: < 5%
Ammonia: < 0.1 micromole/mg
Formulation Lyophilized from sodium citrate and mannitol buffer.
Appearance Tan powder
Recertification 3 years
Storage -20°C
Application Used for the determination of Urea in serum or plasma assays.
Function Glutamate dehydrogenase is used to catalyze the conversion of isocitrate into α-ketoglutarate and carbon dioxide.
Synonyms NAD(P)+, GDH1, L-GDH, GDH, Glutamate dehydrogenase 1, mitochondrial, L-Glutamate:NAD(P)+ oxidoreductase
Molecular Weight ~350,000
CAS Number 9029-12-3
E.C. Number
Gene GLUD1, BOS_24262, GDH
Gene ID 281785
Accession No P00366

Lee Biosolutions is the leading producer of L-Glutamic Dehydrogenase (GLDH) and other animal enzymes for clinical research and bulk for diagnostic manufacturing of liver function tests.

Technical support, bulk quantities and aliquoting available, email for more details.

GLDH is an enzyme, present in mitochondria of eukaryotes, as are some of the other enzymes required for urea synthesis, that converts glutamate to alpha-Ketoglutarate, and vice-versa.

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260-10-1 $ 75.00 1 kU
260-10-10 $ 447.00 10 kU
260-10-100 $ 1,484.00 100 kU
260-10-1,000 Inquire 1,000 kU