Immunoglobulin M (IgM)
Catalogue Number: 340-35
Description
Availability | Discontinued - See 340-31 or 340-39 |
Product Name | Immunoglobulin M |
Source | Human Myeloma Plasma |
Catalogue Number | 340-35 |
Purity | > 95% (SDS-PAGE) |
Form | Liquid |
Protein | 1.0 - 5.0 mg/mL (E0.1%280nm = 1.18) |
Appearance | Clear, colorless liquid |
Formulation | Frozen solution in tris and sodium chloride, pH 8.0 with 0.1% sodium azide. |
Related Products | 340-21 - IgG antigen from human plasma
340-13 - IgA antigen from human plasma 340-41 - IgE antigen from human myeloma plasma |
Storage | -20°C |
Recertification | 2 years |
Infectious Disease Testing | Negative or non-reactive at the donor level for anti-HIV 1 and 2, anti-HCV, HBsAg, HCV NAT and HIV-1 NAT by FDA approved methods. |
Synonyms | IgM |
Molecular Weight | 950,000 |
Applications
Overview
Human Immunoglobulin M (IgM) is available in bulk quantities, from 10,000 mg single lot sizes.
Custom preparations, technical support, bulk quantities and aliquoting available, email Info@leebio.com for more details.
Immunoglobulin M forms polymers where multiple immunoglobulins are covalently linked together with disulfide bonds, normally as a pentamer or occasionally as a hexamer. IgM is by far the physically largest antibody in the circulation. Due to its polymeric nature, it possesses high avidity, and is particularly effective at complement activation.
IgM is the class of immunoglobulin characterized by heavy chains and is the first immunoglobulin to appear on the surface of B cells and the first to be secreted.
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