Ceruloplasmin (Cp)
Product Name | Ceruloplasmin |
Source | Human Plasma |
Catalogue Number | 187-51 |
Purity | > 95% (SDS-PAGE) |
Form | Lyophilized |
Protein | Reported in mg/vial (A280, E0.1%=1.5) |
Formulation | Lyophilized from 50 mM potassium phosphate, 100 mM potassium chloride, 20 mM EACA, and 5 mM EDTA, pH 6.8. |
Related Products | GC-80A - anti-Human Ceruloplasmin (Cp) polyclonal antibody 187-55 - Copper-free Ceruloplasmin from human plasma 270-40 - Ferritin from human liver |
Storage | -20°C |
Recertification | 5 years |
Infectious Disease Testing | Negative or non-reactive at the donor level for anti-HIV 1 and 2, anti-HCV and HBsAg by FDA approved methods. |
Reconstitution | De-ionized water |
Molecular Weight | 132,000 |
Synonyms | CER, CP, CP-2, Ferroxidase, caeruloplasmin |
CAS Number | 9031-37-2 |
E.C. Number | 1.16.3.1 |
Manufacturer Lee Biosolutions produces human plasma Ceruloplasmin for research and bulk manufacturing.
Custom preparations, technical support, bulk quantities and aliquoting available, email Info@leebio.com for more details.
Human Ceruloplasmin (CER) is officially known as ferroxidase or iron(II):oxygen oxidoreductase. CER is an enzyme synthesized in the liver containing 8 atoms of copper in its structure. Although Human CERULOPLASMIN (CER) is often considered a copper transport protein, this is not its primary function, just as human hemoglobin is not a carrier of iron, although it contains iron.
The main carrier for copper in the plasma of humans is albumin. Ceruloplasmin enzyme (ferroxidase) catalyzes the oxidation of ferrous iron (Fe2+) to ferric iron (Fe3+), therefore assisting in Human Ceruloplasmin enzyme transport in the plasma in association with transferrin, which can only carry iron in the ferric state