Cathepsin G
Catalogue Number: 186-10
Description
| Product Name | Cathepsin G |
| Source | Human Neutrophils |
| Catalogue Number | 186-10 |
| Purity | > 90% (SDS-PAGE) |
| Form | Liquid |
| Protein | 1 - 4 mg/mL (Coomassie) |
| Activity | > 5 U/mL |
| Unit Definition | One unit will hydrolyze one micromole of succinyl-alanine-alanine-proline-phenylalanine-p-nitroanilide per minute at 37°C and pH 7.5. |
| Specific Activity | > 5 U/mg protein |
| Formulation | 0.2 micron filtered solution in 0.05 M sodium acetate, 0.8 M sodium chloride, pH 5.5. |
| Appearance | Clear, colorless to light yellow solution |
| Recertification | 2 years |
| Storage | 2-8°C |
| CAS Number | 56645-49-9, 107200-92-0 |
| E.C. Number | 3.4.21.20 |
| Gene | CTSG, CATG, CG |
| Gene ID | 1511 |
| References | 1) Processing of Laminin α Chains Generates Peptides Involved in Wound Healing and Host Defense, J Innate Immun 2014;6:467-484. |
Applications
Overview
Lee Biosolutions is the leading supplier of Human Neutrophil Cathepsin G for medical research and diagnostic manufacturing.
Custom preparations, technical support, bulk quantities and aliquoting available, email Info@leebio.com for more details.
Human Cathepsin G is a serine protease located in the azurophil granules of neutrophils. Studies have shown that when released from granulocytes, Cathepsin G binds to NK cells and augments NK cytotoxicity through its protease activity.
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