Immunoglobulin M (IgM)
Catalogue Number: 340-30
Description
| Product Name | Immunoglobulin M |
| Source | Human Plasma |
| Catalogue Number | 340-30 |
| Purity | > 96% (SDS-PAGE) |
| Form | Lyophilized |
| Protein | Reported in mg/vial (E0.1%280nm= 1.18) |
| Appearance | White to off-white powder |
| Solubility | Clear, colorless to slightly hazy (1 mg/mL phosphate buffered saline) |
| Formulation | Lyophilized from 50mM tris, 200 mM sodium chloride and PEG 6000, pH 8.0. |
| Related Products | 340-13 - IgA antigen from human plasma - Liquid 340-12 - IgA antigen from human plasma - Lyophilized 340-35 - IgM antigen from human myeloma plasma |
| Storage | 2-8°C |
| Recertification | 5 years |
| Infectious Disease Testing | Negative or non-reactive at the donor level for anti-HIV 1 and 2, anti-HCV and HBsAg by FDA approved methods. |
| Synonyms | IgM |
| Molecular Weight | 950,000 |
Applications
Overview
Human Immunoglobulin M (IgM) is available in bulk quantities, from 1,000 mg single lot sizes.
Custom preparations, technical support, bulk quantities and aliquoting available, email Info@leebio.com for more details.
Immunoglobulin M forms polymers where multiple immunoglobulins are covalently linked together with disulfide bonds, normally as a pentamer or occasionally as a hexamer. IgM is by far the physically largest antibody in the circulation. Due to its polymeric nature, it possesses high avidity, and is particularly effective at complement activation.
IgM is the class of immunoglobulin characterized by heavy chains and is the first immunoglobulin to appear on the surface of B cells and the first to be secreted.
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Lee Biosolutions, Inc
