Thyroid Stimulating Hormone (TSH)
| Product Name | Thyroid Stimulating Hormone antigen |
| Source | Human Pituitary Glands |
| Catalogue Number | 996-51 |
| Purity | > 95% (SDS-PAGE) |
| Form | Lyophilized |
| Activity | > 5 IU/mg (WHO 2nd IRP 80/558) |
| Contaminants | FSH: < 0.5% hGH: < 0.1% LH: < 1.0% PRL: < 0.1% |
| Formulation | Lyophilized from 50 mM ammonium bicarbonate. |
| Reconstitution | Neutral pH buffer of choice. Avoid extreme high and low pH |
| Related Products | 996-11 - FSH antigen from human pituitary gland 996-31 - LH antigen from human pituitary gland 996-21 - hGH antigen from human pituitary gland |
| Storage | -20°C |
| Recertification | 5 years |
| Infectious Disease Testing | Negative or non-reactive at the donor level for anti-HIV 1 and 2, anti-HCV, HBsAg, HCV NAT, HIV-1 NAT and syphilis by FDA approved methods. |
| Synonyms | TSH, Thyrotropin |
| CAS Number | 9002-71-5 |
| Molecular Weight | 28,000 |
Lee Biosolutions offers High Purity Thyroid Stimulating Hormone (TSH) for clinical research and IVD bulk manufacturing.
FOR LABORATORY AND MANUFACTURING USE ONLY AND NOT FOR USE IN HUMANS
Technical support, bulk quantities and custom buffers and aliquoting available, email Info@leebio.com for more details.
Thyroid-stimulating hormone (also known as TSH or thyrotropin) is a peptide hormone synthesized and secreted by thyrotrope cells in the anterior pituitary gland which regulates the endocrine function of the thyroid gland. TSH is a glycoprotein and consists of two subunits, the alpha and the beta subunit.
The TSH test is often the test of choice for evaluating thyroid function and/or symptoms of hyperthyroidism or hypothyroidism. It is frequently ordered along with or preceding a T4 test. Other thyroid tests that may be ordered include a T3 test and thyroid antibodies (if autoimmune-related thyroid disease is suspected).
according to Labtest online: A high TSH result often means an underactive thyroid gland that is not responding adequately to the stimulation of TSH due to some type of acute or chronic thyroid dysfunction. Rarely, a high TSH result can indicate a problem with the pituitary gland, such as a tumor producing unregulated levels of TSH. A high value can also occur when someone with a known thyroid disorder or who has had their thyroid gland removed is receiving too little thyroid hormone medication.
A low TSH result can indicate an overactive thyroid gland (hyperthyroidism) or excessive amounts of thyroid hormone medication in those who are being treated for an underactive (or removed) thyroid gland. Rarely, a low TSH result may indicate damage to the pituitary gland that prevents it from producing adequate amounts of TSH.
Lee Biosolutions, Inc
