Prolactin (PRL)
| Product Name | Prolactin |
| Source | Human Pituitary Glands |
| Catalogue Number | 996-41 |
| Purity | > 98% (SDS-PAGE) |
| Form | Lyophilized |
| Activity | > 21 IU/mg |
| Contaminants | TSH: < 0.1% FSH: < 0.1% LH: < 0.1% hGH: < 0.1% |
| Formulation | Lyophilized from 50 mM ammonium bicarbonate. |
| Reconstitution | Neutral pH buffer of choice. Avoid extreme high and low pH |
| Pairing Information | Capture Ab: 996-42 - anti-Human Prolactin Monoclonal Antibody Detection Ab: 996-43 - anti-Human Prolactin Monoclonal Antibody Antigen: 996-41 - Prolactin from human pituitary gland |
| Storage | -20°C |
| Recertification | 5 years |
| Infectious Disease Testing | Negative or non-reactive at the donor level for anti-HIV 1 and 2, anti-HCV, HBsAg, HCV NAT, HIV-1 NAT and syphilis by FDA approved methods. |
| Synonyms | Luteotropic Hormone, LTH, PRL |
| Molecular Weight | ~23,000 |
| CAS Number | 9002-62-4 |
Lee Biosolutions is the leading producer and supplier of high quality native human Prolactin Hormone.
FOR LABORATORY AND MANUFACTURING USE ONLY AND NOT FOR USE IN HUMANS
Technical support, bulk quantities and custom buffers and aliquoting available, email Info@leebio.com for more details.
Prolactin is an integral member of the immunoneuroendocronology network and appears to have a role in pathogenesis of autoimmune diseases (Ref: DOI: 10.1007/s12016-009-8185-3).
During pregnancy, high circulating concentrations of estrogen and progesterone inhibit the action of prolactin on milk production. Following delivery, reduced estrogen and progesterone production allows prolactin to induce lactation. Current studies have suggested that there is increasing evidence supporting the role of prolactin in human breast and prostate tumorogenesis, especially when it is locally-produced.(ref:Endocrine Abstracts (2011) 26 MTE11)
Prolactin is a hormone released by the pituitary gland that stimulates breast development and milk production in women. There is no known normal function of prolactin in men.
Prolactin is usually measured when checking for pituitary tumors and the cause of: Breast milk production that is not related to childbirth (galactorrhea), Impotence, Infertility, Irregular or no menstrual periods (amenorrhea).
Lee Biosolutions, Inc
