Lactoferrin (hLf)

Catalogue Number: 390-30
Availability Discontinued, replaced with item 390-30R
Product Name Lactoferrin
Source Human Neutrophils
Catalogue Number 390-30
Purity > 96% (SDS-PAGE)
Form Liquid
Protein > 1.0 mg/mL (Lowry)
Storage 2-8°C
Appearance Pink liquid
Synonyms hLF, LTF, LF, Lactotransferrin
Contaminants No detectable MPO
Form Liquid in 0.05M Sodium Acetate, 0.15 NaCl
Recertification 2 years
Molecular Weight ~77,000
pH 6.0
UNSPSC code 51131907

Lee Biosolutions produces high purity human Neutrophil Lactoferrin for IVD manufacturing or research use.

Custom preparations, technical support, bulk quantities and aliquoting available, email for more details.

Lactoferrin (hLF) is an iron-binding glycoprotein that facilitates the production of hydroxyl radicals and chelates iron, preventing its accessibility to microorganisms and thus inhibiting growth. It is found in secondary granules in polymorphonuclear neutrophils, lacking terminal fucose residues in the glycan chains that are required for binding to macrophages.

Lactoferrin plays an important role in iron transport and utilization in humans. A glycoprotein containing about 6% sugar and having a total molecular weight of about 77kDa, and is capable of binding two ferric ions with high affinity. Although lactoferrin binds iron tightly, the binding is reversible so that the metal is available upon demand to cells with a need for this essential element. Each human lactoferrin molecule has two iron-binding domains.

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390-30-1 Inquire 1 mg