Ferritin
Product Name | Ferritin |
Source | Human Liver |
Catalogue Number | 270-41 |
Purity | > 98% (SDS-PAGE) |
Form | Liquid |
Protein | 3 - 6 mg/mL (Lowry) |
Formulation | Solution in tris buffered sodium chloride, pH 7.5, with bromo-nitro-dioxane and methylisothiazolone as preservatives. |
Appearance | Clear, reddish-brown solution |
Pairing Information | Capture Ab: 270-43 - anti-Human Liver Ferritin Monoclonal Antibody Detection Ab: 270-44 - anti-Human Liver Ferritin Monoclonal Antibody Antigen: 270-40 - Ferritin from human liver |
Storage | 2-8°C |
Recertification | 2 years |
Infectious Disease Testing | Negative or non-reactive at the donor level for anti-HIV 1 and 2, anti-HCV and HBsAg by FDA approved methods. |
Molecular Weight | 440,000 |
Synonyms | FTL |
CAS Number | 9007-73-2 |
Accession No | P02792 |
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Ferritin is a globular protein complex consisting of 24 protein subunits and is the primary intracellular iron-storage protein in both prokaryotes and eukaryotes, keeping iron in a soluble and non-toxic form.
Human Ferritin is a globular protein found mainly in the liver, which can store about 4500 iron ions in a hollow shell made of 24 identical subunits. Inside the human ferritin shell, iron ions form crystallites together with phosphate and hydroxide ions.
Human Serum ferritin levels are measured in patients as part of the iron studies workup for anemia and for restless leg syndrome. Human ferritin levels have a direct correlation with the total amount of iron stored in the body. Human Ferritin level(s) are also indicative of the erosion of iron stores during pregnancy.