Luteinizing Hormone (LH)
| Product Name | Luteinizing Hormone |
| Source | Human Pituitary Glands |
| Catalogue Number | 996-31 |
| Purity | > 98% (SDS-PAGE) |
| Form | Lyophilized |
| Activity | > 8,500 IU/mg |
| Contaminants | FSH: < 18.75 IU/mg (All assayed < 0.1% w/w) TSH: < 0.0425 IU/mg PRL: < 0.005 mg/mg hGH: < 0.005 mg/mg |
| Formulation | Lyophilized from 50 mM ammonium bicarbonate |
| Reconstitution | Reconstitute using neutral pH buffer of choice. Avoid extreme high and low pH |
| Related Products | 996-11 - FSH antigen from human pituitary gland 996-21 - hGH antigen from human pituitary gland 996-51 - TSH antigen from human pituitary gland |
| Storage | -20°C |
| Recertification | 5 years |
| Infectious Disease Testing | Negative or non-reactive at the donor level for anti-HIV 1 and 2, anti-HCV, HBsAg, HCV NAT, HIV-1 NAT and syphilis by FDA approved methods. |
| Molecular Weight | ~30,000 |
| Synonyms | LH, Lutropin, Interstitial Cell-Stimulating Hormone |
| References | 1) Confirmation of luteinizing hormone (LH) in living human vitreous and the effect of LH receptor reduction on murine electroretinogram, Neuroscience, June 2018. |
Lee Biosolutions is the leading supplier of Human Luteinizing Hormone for research and clinical diagnostic manufacturing.
Technical support, bulk quantities and aliquoting available, email Info@leebio.com for more details.
Luetinzing Hormone (LH) also known as lutropin is a heterodimeric glycoprotein. Each monomeric unit is a glycoprotein molecule; one alpha and one beta subunit make the full, functional protein. Luteinizing Hormone is essential for reproduction in both males and females.
According to Labtest online: LH is often used in conjunction with other tests (FSH, testosterone, estradiol and progesterone) in the workup of infertility in both men and women. Luteinizing Hormone levels are also useful in the investigation of menstrual irregularities and to aid in the diagnosis of pituitary disorders or diseases involving the ovaries or testes.
In children, FSH and LH are used to diagnose delayed and precocious (early) puberty.
Luteinzing Hormone is sometimes measured in relation to gonadotropin releasing hormone (GnRH) to distinguish between primary or secondary disorders involving the hypothalamus, pituitary gland, or the gonads. GnRH is the hormone produced by the hypothalamus that stimulates the pituitary to release LH and FSH. For this test, a baseline blood sample is drawn and then the patient is given an injection of GnRH. Subsequent blood samples are drawn at specified times and the level of LH is measured. This test can help differentiate between disease of the ovaries or testes (primary) and a disorder of the pituitary or hypothalamus (secondary).
Lee Biosolutions, Inc
