Thyroglobulin (Tg)
| Product Name | Thyroglobulin |
| Source | Human Thyroid Gland |
| Catalogue Number | 528-11 |
| Purity | > 96% (Native PAGE) |
| Form | Lyophilized |
| Protein | Reported in mg/vial (A280, E0.1%=1.04) |
| Formulation | Lyophilized from 20 mM ammonium bicarbonate. May contain traces of buffer salts. |
| Appearance | White to off-white powder |
| Reconstitution | Use of a phosphate buffer, pH > 7.0 containing 0.15 M sodium chloride. |
| Pairing Information | Capture Ab: 528-14 - anti-Human Thyroglobulin Monoclonal Antibody Detection Ab: 528-15 - anti-Human Thyroglobulin Monoclonal Antibody Antigen: 528-11 - Thyroglobulin from human thyroid gland |
| Storage | 2-8°C |
| Recertification | 5 years |
| Infectious Disease Testing | Negative or non-reactive at the donor level for anti-HIV 1 and 2, anti-HCV, HBsAg and Syphilis by FDA approved methods. |
| Molecular Weight | 660,000 |
| Synonyms | Tg |
| CAS Number | 9010-34-8 |
| Accession No | P01266 |
| Gene | TG |
Lee Biosolutions is the leading supplier of human Thyroglobulin (Tg) for clinical research and diagnostic manufacturing.
Custom preparations, technical support, bulk quantities and aliquoting available, email Info@leebio.com for more details.
Thyroglobulin is a 660 kDa, dimeric protein produced by and used entirely within the thyroid gland and was referred to as a "colloid". Human Tg is used by the thyroid gland to produce the thyroid hormones thyroxine (T4) and triiodothyronine.
Patients with Hashimoto's thyroiditis or Graves' disease, frequently develop antibodies against human Thyroglobulin (Tg). Human Thyroglobulin specific antibodies help in the diagnosis of these diseases, but they also may be present in apparently healthy euthyroid individuals.
Human Thyroglobulin levels in the blood can be used as a tumor marker for certain kinds of thyroid cancer and levels in the blood can also be elevated in cases of Graves disease.
Lee Biosolutions, Inc
