Pepsinogen II (PGII, PGC)

Product Name Pepsinogen II
Source Human Gastric Mucosa
Catalogue Number 440-52
Purity > 90% (SDS-PAGE)
Purity Note Typically > 96% (SDS-PAGE)
Form Lyophilized
Protein Reported mg protein/vial (A280nm, E0.1%=1.43)
Specific Activity > 1,000 U/mg protein (After activation)
Unit Definition One unit will produce a change in A280 of 0.001 per minute at pH 2.0 and 37°C, measured as TCA-soluble products from hemoglobin.
Appearance White to off-white powder
Solubility Clear, colorless liquid (1 mg/mL 0.02 M tris-cholride, pH 8.0)
Reconstitution After reconstitution maintain at or above pH 8.0 to avoid activation.
Formulation Lyophilized from tris-chloride, pH 8.5
Related Products 440-50 - Pepsinogen I from human gastric mucosa
441-10 - Pepsin 1:10,000 from porcine gastric mucosa
435-10 - Mucin from porcine gastric mucosa
Recertification 3 years
Storage -20°C
Infectious Disease Testing Negative or non-reactive at the donor level for anti-HIV 1 and 2, anti-HCV and HBsAg by FDA approved methods.
Molecular Weight 40,600
Synonyms Pepsinogen C, PG II, PGC, Gastricsin, Pepsinogen 2
E.C. Number
Gene PGC, RP11-298J23.1, PEPC, PGII
Gene ID 5225
Accession No P20142